During a fire in 1710 most of the church's interior was destroyed. Therefore an entirely new sanctuary room was created. The interior was designed with an 18th century style and is one of the most well-preserved interiors from this period in Norway. It was repainted on several occasions, but today is characterised by the marbling and landscapes painted by Gottfried Ezekiel, a German painter who resided in Bergen. He also performed work in several churches in Nordland - Bodin, Nesna, Beiarn, Saltdal and Flakstad.

Pews were installed in the sanctuary room and a gallery was added towards the west and in the east wing. Moreover rich families built family "theatre boxes" or enclosed pews, many of which are still preserved today.

The organ was built by Amund Eriksen in Kristiania, and set up in Gildeskål by Claus Jensen in 1865. The organ was moved to the new church in 1881, and used until 1986. It was restored and set up again in the old church in 1992.